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Tyler Liban
Protein Biochemist - R&D Scientist - Structural Biologist - Method Development - Biophysics
Professional Background
Tyler Liban is a highly skilled protein scientist with over ten years of experience in the field of biochemical research and protein design. He possesses a remarkable proficiency in the design, purification, and characterization of target molecules, which are critical for assessments in biochemical studies, bioassays, and in vivo models. Tyler currently occupies the role of Senior Scientist at Gensun Biopharma, where he is deeply involved in the development of purification strategies and analytical methods for a diverse array of biological molecules, including antibodies and engineered proteins. His expertise extends to bi- and tri-specific molecules, making him an indispensable asset in the pursuit of novel therapeutics, particularly in the burgeoning field of immuno-oncology.
Throughout his career, Tyler has demonstrated a profound commitment to advancing the science of therapeutics. His work involves not only rigorous scientific methods but also a passion for exploring innovative solutions to complex biological challenges. His approach combines both biochemical and biophysical techniques that drive forward the development of impactful immuno-oncology therapies.
Tyler's previous positions have paved the way for his current role, allowing him to cultivate a comprehensive understanding of protein science. He has held the position of Scientist in Protein Sciences at Gensun Biopharma, where he made significant contributions to the development of new treatment modalities. Additionally, he worked as a Structural Biologist and Postdoctoral Research Fellow at the prestigious Fred Hutchinson Cancer Research Center, where he honed his skills in experimental structural determination and protein modeling.
Education and Achievements
Tyler pursued his Doctor of Philosophy (Ph.D.) in Chemistry at the University of California, Santa Cruz, a renowned institution known for its rigorous academic curriculum and innovative research. His doctoral studies provided him with a strong foundation in both theoretical and practical aspects of chemical and protein sciences. Earlier, he achieved his Bachelor of Science (B.S.) degree in General Biology from the University of Wisconsin-Madison, where he first developed an interest in the biological sciences and the intricate workings of proteins.
In his academic journey, Tyler engaged in various research initiatives, starting as an Undergraduate Research Assistant at the University of Wisconsin-Madison. This early exposure enabled him to gain first-hand experience in laboratory techniques and solidified his decision to pursue a career in protein science. His exceptional performance and dedication led him to advance to more sophisticated roles in research.
Technical Skills and Expertise
Tyler exhibits an extensive array of technical skills essential for modern biochemical research. He is proficient in multiple protein purification techniques including affinity chromatography (Protein A), size exclusion chromatography (SEC), ion exchange chromatography (IEX), and hydrophobic interaction chromatography (HIC) using advanced AKTA FPLC systems. Such proficiency underpins his ability to isolate and characterize proteins with high precision.
Moreover, Tyler is adept at characterizing protein-protein and protein-small molecule interactions through a variety of sophisticated techniques, such as Enzyme-Linked Immunosorbent Assay (ELISA), Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), and Fluorescence Polarization (FP). He also utilizes Octet-BLI technology to monitor interactions in real-time, which is critical for the development of effective therapeutics.
Additionally, Tyler possesses experience across multiple expression systems, including E. coli, yeast, and mammalian tissue culture. His ability to enzymatically modify proteins further complements his skillset, allowing him to conduct functional assays and high-throughput screening with efficacy.
His expertise also encompasses protein modeling and structural determination, where he applies advanced methodologies such as X-ray crystallography, utilizing software like COOT, Phenix, and PyMOL. He is also skilled in electron microscopy techniques, which are invaluable for visualizing protein structures and interactions on a molecular level.
Achievements
Throughout his career, Tyler Liban has achieved notable milestones that reflect his dedication to protein science and therapeutic development. His impressive body of work contributes significantly to the growing field of immuno-oncology, where innovative therapies are urgently needed to combat cancer. At Gensun Biopharma, he has played a pivotal role in pushing the boundaries of what is possible within protein engineering and therapeutic development, leading to advancements that hold promise for future treatments.
With a background grounded in rigorous academia and a career defined by impactful research, Tyler has positioned himself as a leader in protein science. His ongoing work at Gensun Biopharma not only highlights his expertise but also showcases his commitment to making a substantial difference in health and therapeutic outcomes through his scientific endeavors. In a landscape filled with challenges and opportunities, Tyler continues to embody the spirit of innovation and scientific advancement in the field of protein sciences.
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