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Leslie Crews
Assistant Professor of Medicine, Division of Regenerative Medicine
Leslie Crews is an accomplished Assistant Professor of Medicine at the University of California, San Diego (UCSD), specializing in the Division of Regenerative Medicine. Her research primarily focuses on stem cell biology, translational cancer research, and specifically, multiple myeloma, a type of blood cancer.
Education and Academic Background
Dr. Crews earned her Bachelor's degree in Microbiology, Immunology, and Molecular Genetics from the University of California, Los Angeles (UCLA). She then completed her PhD in Molecular Pathology at UCSD in 2010. Following her doctoral studies, she undertook postdoctoral training in leukemia and myeloma research, where she contributed significantly to understanding the role of the RNA editing gene ADAR1 in disease progression and drug resistance in multiple myeloma.12
Research Contributions
Since establishing her independent laboratory in 2017, Dr. Crews has focused on exploring the molecular mechanisms underlying multiple myeloma initiation and progression. Her work aims to identify novel therapies that can more effectively target this incurable cancer. She has co-authored over 65 peer-reviewed manuscripts, accumulating more than 12,000 citations, and her research has been recognized with various awards, including the Leukemia & Lymphoma Society Scholar Award.124
Dr. Crews has also been appointed as the Co-Leader of the Hematologic Malignancies Research Program at Moores Cancer Center, further highlighting her leadership role in cancer research.2 Her laboratory employs innovative human cell-based models and molecular assays to develop new diagnostic and therapeutic technologies for cancer treatment.34
Professional Affiliations and Impact
In addition to her research, Dr. Crews is actively involved in various academic leadership roles and community outreach programs aimed at improving cancer care and education. She has received significant funding for her research endeavors, including an NCI R37 grant aimed at advancing understanding and treatment of multiple myeloma.23
Overall, Leslie Crews is a prominent figure in regenerative medicine and cancer research, contributing to both scientific knowledge and practical advancements in treating blood cancers.