Suggestions
Karen Hedin
Professor of Immunology, Principal Investigator at Mayo Clinic College of Medicine and Science, Scottsdale, Arizona
Professional Background
Karen Hedin, a distinguished leader in the fields of biochemistry and immunology, has made remarkable strides in research and education throughout her extensive career. With a Ph.D. in Biochemistry conferred by the prestigious University of Washington in Seattle, her journey began under the mentorship of the esteemed Roger M. Perlmutter. Under her previous name, Karen E. Chaffin, she immersed herself in advanced studies that would lay the groundwork for her future innovative contributions.
Following her doctorate, Dr. Hedin completed two significant postdoctoral fellowships at the renowned Mayo Clinic, where she specialized in Pharmacology and later in Immunology. At Mayo, she delved into critical areas such as G protein-regulated cardiac ion channels under the guidance of David E. Clapham, followed by research in T lymphocyte signal transduction led by David J. McKean. These experiences not only honed her technical skills but also ignited her passion for understanding complex biological systems, specifically those pertaining to cancer and immune disorders.
Renowned for her research excellence, Dr. Hedin was awarded her first R01 NIH research grant in 1999. This crucial funding propelled her to establish a forward-thinking, NIH-, foundation-, and industry-funded research program focused on studying G protein coupled receptors (GPCR) and chemokine receptor signal transduction. Her work is especially relevant to developing treatments and strategies to combat cancer and various immune disorders. Over a span of 17 years, she has been the Principal Investigator of multiple NIH R01 grants, firmly establishing herself as a pivotal figure in the fields of chemokines and cancer.
In addition to her research endeavors, Dr. Hedin is an active contributor to the academic community, often invited to review research grants for the NIH. Her commitment to mentorship and training is evident through her sustained involvement in guiding numerous trainees within her lab, including many promising under-represented minority students (URM). In February 2019, she relocated her laboratory from the Mayo Clinic in Minnesota to the Mayo Clinic in Arizona as part of the institution's ambitious expansion in the Phoenix area.
Education and Achievements
Dr. Hedin's extensive educational contributions reflect her dedication to fostering the next generation of scientists. In her dual role as a seasoned researcher and educator, she has taken on multiple leadership positions within the Mayo Clinic Graduate School of Biomedical Sciences over the past fifteen years. Recognized for her contributions, she currently serves as a standing member of the NIH TWC-D, a body dedicated to reviewing biomedical research training grants targeted towards under-represented and minority students.
Among her many accomplishments, Dr. Hedin has successfully co-PI'd and co-directed two NIH NIGMS R25 diversity research training programs aimed at Ph.D. and post-baccalaureate/pre-Ph.D. training for URMs for over a decade. Her dedication to educational equity is further exemplified through her five-year tenure as Associate Director of Education for the Mayo Clinic Center for Regenerative Medicine. During this time, she developed the innovative Regenerative Sciences Training Program (RSTP), a new Ph.D. initiative designed to train future leaders in regenerative medicine. In addition, she demonstrated robust leadership as the Graduate Program Director of RSTP for two years.
Dr. Hedin's contributions to the academic sphere are also evident through her five-year directorship of the Mayo Clinic Immunology Ph.D. Training Program. Approximately one-third of trainees in this distinguished program receive vital support through the NIH T32 grant, while the remainder benefit from fellowships and institutional funding from the Mayo Clinic. Such programs reflect her commitment to promoting diversity and excellence in biomedical training.
Achievements
Throughout her illustrious career, Karen Hedin has accumulated numerous accolades and achievements that underscore her influence and leadership within the fields of biochemistry and immunology. Her research has not only advanced scientific understanding but has also paved the way for new therapeutic strategies in cancer treatment and immune disorders.
In total, Dr. Hedin has overseen 17 years of NIH R01 funding, guiding her research lab toward groundbreaking discoveries in chemokine biology. Her ability to secure funding consistently over the years highlights not only her expertise but her ingenuity and capacity to address critical research questions. Furthermore, her involvement with NIH as a reviewer showcases her recognition as a thought leader, trusted by peers and the funding body alike.
Moreover, her commitment to mentorship is reflected in the success of her trainees, many of whom have gone on to make significant contributions in their own right. By fostering an inclusive and supportive lab environment, Dr. Hedin has nurtured a new wave of diverse scientists, ensuring that the next generation is equipped to tackle the complexities of biomedical research with empathy and expertise.
In summary, Karen Hedin's career is characterized by a profound commitment to research innovation, educational leadership, and mentorship. Her journey from the University of Washington to the Mayo Clinic's cutting-edge initiatives illustrates a dedication to advancing the fields of biochemistry and immunology, with a keen focus on inclusivity and diversity in science. Whether through her impactful research or her unwavering support for underrepresented minorities in academia, Dr. Hedin stands as a model of excellence in the scientific community.