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    Eric Toone

    Professor of Chemistry (Emeritus) at Duke University

    Professional Background

    Dr. Eric Toone is a distinguished chemist who has made substantial contributions to both academia and the pharmaceutical industry throughout his impressive career. With a Ph.D. in Organic Chemistry from the University of Toronto, which he earned in 1988, he has cultivated a vast amount of knowledge and expertise in his field. After completing post-doctoral studies under the mentorship of the renowned Professor George Whitesides at Harvard University, Dr. Toone embarked on his independent academic career at Duke University in 1990, where he has since thrived as a Professor of Chemistry and Biochemistry.

    Dr. Toone's professional journey is marked by prolific authorship, with over 220 original papers, reviews, book chapters, and abstracts published in the disciplines of physical organic and biophysical chemistry. His innovative work is recognized globally, and he holds more than 20 patents across various biomedical fields, showcasing his commitment to advancing scientific research and application. As a scientific founder of three research-based pharmaceutical companies, including Aerie Pharmaceuticals, Vindica Pharmaceuticals, and Valanbio Therapeutics, he has significantly contributed to the development of cutting-edge therapies for conditions such as glaucoma and antibiotic-resistant infections.

    Notably, from 2009 to 2012, Dr. Toone took on a transformative role at the U.S. Department of Energy's Advanced Research Projects Agency - Energy (ARPA-E). As the Program Director and Deputy Director for Technology, he led key initiatives to propel innovation in clean energy technologies, ultimately taking on the role of Agency Leader in 2012. This pivotal role allowed Dr. Toone to impact policy and strategic direction in energy research and development.

    In 2013, he returned to Duke University as Vice Provost and Director of the Duke University Innovation and Entrepreneurship Initiative, where he played a vital role in nurturing the entrepreneurial spirit across the university community. His leadership in this position spanned until May 2017, further reinforcing his dedication to fostering innovation.

    Today, Dr. Toone serves as the Executive Managing Director for Technology at Breakthrough Energy Ventures, a $1 billion investment fund established by the Breakthrough Energy Coalition. This coalition, assembled by Bill Gates, focuses on advancing clean energy technologies to address the pressing challenges of climate change and sustainability. Dr. Toone's position at Breakthrough Energy Ventures allows him to continue influencing the development and adoption of sustainable energy solutions on a global scale.

    Education and Achievements

    Dr. Toone's academic journey began with a Bachelor of Science (B.Sc.) in Chemistry from the University of Guelph, followed by a Master of Science (M.Sc.) and a Ph.D., both specializing in Organic Chemistry, from the University of Toronto. The strong foundation built during his studies laid the groundwork for his extensive contributions to chemistry and biochemistry. His postdoctoral fellowship at Harvard further enriched his expertise and network within the scientific community.

    Among his remarkable achievements, Dr. Toone's role in founding and advising three pharmaceutical companies stands out. Aerie Pharmaceuticals has made significant strides in ophthalmology, specifically in developing treatments for glaucoma, while Vindica Pharmaceuticals focuses on nitric oxide-based therapies, addressing critical health challenges. Valanbio Therapeutics is at the forefront of antibiotic development, working diligently to create therapeutics for Gram-negative organisms, an area of crucial significance given the rise of antibiotic resistance.

    During his tenure at ARPA-E, Dr. Toone was instrumental in shaping the agency's strategies to foster innovation in energy technologies, driving significant advancements in how the United States approaches energy research. His leadership and foresight during this period have left a lasting impact on the agency’s mission and goals, aligning with his passion for sustainable energy solutions.

    Key Contributions

    In terms of specific achievements within his academic and professional career, Dr. Toone's many publications highlight his prolific output and influence in the scientific community. His published works often tackle intricate problems within physical organic and biophysical chemistry, offering insights that have propelled the field forward. His patents, which exceed 20 in number, underscore his ability to navigate complex biomedicine challenges, turning innovative ideas into tangible solutions with practical applications.

    Furthermore, Dr. Toone's leadership roles have consistently demonstrated his commitment to innovation. As Vice Provost and Director of the Duke University Innovation and Entrepreneurship Initiative, he championed a culture of creativity and entrepreneurship within the academic landscape, helping to bridge the gap between research and real-world applications. This initiative has significantly increased opportunities for students and faculty to engage in entrepreneurial ventures.

    In his current role at Breakthrough Energy Ventures, Dr. Toone is at the intersection of technology, investment, and sustainability, positioning him to influence the creation and scaling of clean energy technologies that will define the future of energy consumption and production. His work aligns with global efforts to combat climate change and promote sustainable practices, further reinforcing his status as a leading figure in the intersection of science and entrepreneurship.

    Overall, Dr. Eric Toone’s extensive background in chemistry, innovation, and entrepreneurship, coupled with his leadership in scientific research and industry initiatives, defines him as a prominent contributor to both science and society. His dedication to advancing clean energy technologies and fostering innovation makes him an influential force in today’s challenges, shaping a more sustainable future through his commitment to research and entrepreneurship.

    Related Questions

    How did Dr. Eric Toone develop his expertise in organic chemistry and biochemistry?
    In what ways has Dr. Toone's experience at the U.S. Department of Energy influenced his current role at Breakthrough Energy Ventures?
    What key themes have emerged in Dr. Toone's research and publications over his career in chemistry?
    How has Dr. Eric Toone contributed to the field of clean energy through his roles in various companies and initiatives?
    What impact did Dr. Toone have on entrepreneurship at Duke University during his tenure as Vice Provost?
    Eric Toone
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    Location

    Durham, North Carolina, United States