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    Xiaojun Liu

    Principal Scientist, AAV Engineering, Process Development, RNA Editing, Drug Discovery at EdiGene Inc.

    Professional Background

    Xiaojun Liu is an accomplished and innovative scientist specializing in gene therapy, with an extensive and rich background spanning over 15 years. Driven by a passion for enhancing the accessibility and reliability of gene therapies, Liu has dedicated his career to making significant advances in the space of viral (including AAV, lentivirus, adenovirus, and herpes simplex virus) and non-viral vectors. Under Liu's leadership, numerous gene therapy projects have been translated from initial concepts to IND enabling stages, laying the groundwork for the future of therapeutic advancements.

    Liu's research has culminated in over 40 peer-reviewed publications in reputable journals such as Cell Metabolism and Circulation Research, garnering upwards of 6,500 citations. His work has been paramount in the identification of seven novel potential therapeutics, showcasing his expertise in cardiovascular and muscular disease. Moreover, his combination of research and drug discovery experience has proven invaluable in securing more than $10 million in research grants and managing over 10 diverse projects.

    With a multitasking approach and results-driven mindset, Liu excels as a project and team leader, demonstrating his capability to thrive in collaborative environments while adhering to strict timelines. His excellent interpersonal communication skills, coupled with remarkable organizational capabilities, have facilitated his success in supervising over 20 junior personnel while also engaging internationally through 18 conference presentations.

    Education and Achievements

    Xiaojun Liu possesses a robust educational foundation, having achieved a Ph.D. in Genetics from Fudan University, as well as a Master of Science and Bachelor of Science in Genetics and Biotechnology, respectively, from Sichuan University. His academic endeavors have equipped him with a profound understanding of genetic principles that inform his current work in gene therapy and drug discovery.

    In terms of achievements, Liu has published a significant number of influential peer-reviewed articles and presented at various international conferences, where he has shared his insights on advanced topics related to gene therapy and molecular biology. Furthermore, his role as an associate editor and editorial board member for Molecular Biotechnology at Springer Publishing demonstrates his commitment to advancing scientific collaborations and discussions in the field.

    Specialties and Skills

    Xiaojun Liu's extensive list of specialties includes expertly navigating AAV, gene therapy, process development, and oligonucleotide therapeutics, along with rare and complex diseases related to cardiovascular and muscular health. Moreover, his expertise in molecular and cellular techniques, particularly microRNAs and genome editing, has made significant contributions towards enhanced therapeutic approaches.

    His technical skill set encompasses a diverse array of methodologies such as qPCR, droplet digital PCR (ddPCR), vector cloning, gene synthesis, CRISPR-Cas technology, RNA sequencing, and much more. Additional competencies extend to various processes in cell culture, bioprocess development, analytical development, and data analysis including bioinformatics using R. Liu demonstrates extensive proficiency in working with animal models and executing preclinical animal studies that are crucial for validating new therapeutic approaches.

    Achievements

    • Over 40 peer-reviewed papers published, with a citation count exceeding 6,500
    • Identification of 7 novel potential therapeutics in the gene therapy domain
    • Led the execution of 10+ projects across the gene therapy sector
    • Secured 9 major research grants amounting to over $10 million
    • Presented at 18 international conferences, enhancing collaboration and knowledge exchange within the scientific community
    • Reviewed 150+ manuscripts for over 20 reputable scientific journals, showcasing his dedication to the research community
    • Managed CROs and CDMOs to ensure project visions are executed with precision and quality

    Xiaojun Liu’s exceptional contributions to gene therapy and drug discovery exemplify the impact of dedicated and passionate researchers in tackling complex health challenges. With his comprehensive expertise and a drive for innovation, Liu is poised to continue leading groundbreaking research that paves the way for developing effective and transformative therapies that can change lives.

    Related Questions

    How did Xiaojun Liu develop his expertise in gene therapy and drug discovery?
    What motivated Xiaojun Liu to focus on making gene therapies more accessible and reliable?
    Can Xiaojun Liu share examples of his innovative approaches in viral vector engineering?
    What has been Xiaojun Liu's most significant breakthrough in the field of cardiovascular and muscular disease?
    How does Xiaojun Liu manage collaboration and team dynamics in his research projects?
    What role does communication play in Xiaojun Liu's management of junior personnel and research collaborations?
    How has Xiaojun Liu's extensive research background influenced his development of therapeutics?
    What are Xiaojun Liu's future aspirations within the field of gene therapy and biotechnology?
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    Location

    Greater Boston