Robert Mallis

Director of Structure Based Protein Engineering at Dana-Farber Cancer Institute

Robert Mallis is the Director of Structure Based Protein Engineering at the Dana-Farber Cancer Institute in Boston, Massachusetts. He holds a Ph.D. and is also an Instructor at Harvard Medical School. His research primarily focuses on T-cell biology, specifically the development and function of T-cell receptors (TCRs) and their applications in immunotherapy for cancer treatment.

Professional Background

Current Position: Director of Structure Based Protein Engineering at Dana-Farber Cancer Institute.
Academic Role: Instructor at Harvard Medical School.
Research Interests:
- T-cell and thymocyte development.
- Mechanobiology of T-cell receptor interactions.
- Development of TCR-based therapies for cancer.

Research Contributions

Mallis has contributed to significant studies regarding T-cell performance, including a recent investigation into how physical forces can enhance T-cell immune responses. This research aims to improve the efficacy of immunotherapies by better understanding the mechanobiological aspects of TCR interactions with antigens on cancer cells.1 2 4

Publications and Impact

He has authored several publications in the field of biochemistry and immunology, contributing to advancements in understanding how T-cells recognize and respond to cancerous cells. His work is supported by various NIH grants aimed at enhancing translational science in cancer treatment.1 3 5

For more details about his professional background, you can view his LinkedIn profile under the username robert-mallis-74535826.