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Prashni Paliwal
Director, Quantitative Sciences at Flatiron Health
Professional Background
Prashni Paliwal is a highly accomplished statistician specializing in clinical development, with a distinguished career centered around oncology and hematology clinical trials. Over the years, she has amassed extensive experience leading Phase I through Phase III trials, solidifying her reputation as a leader in the field of biostatistics. With a proven track record of success, Prashni is particularly noted for her ability to navigate the complexities of clinical trial design and execution, making significant contributions to the development of innovative therapies.
Currently, Prashni serves as the Director of Quantitative Sciences at Flatiron Health, where she utilizes her analytical expertise to drive the development of groundbreaking treatments for cancer patients. Her role focuses on employing advanced statistical methodologies to enhance clinical trial design and analysis, contributing to the optimization of treatment efficacy and safety.
Prior to her current position, Prashni served as the Director of Biostatistics at Cara Therapeutics, where she played a key role in advancing the company’s research initiatives through rigorous biostatistical support. Her experience at Bristol-Myers Squibb, where she held several significant positions including Associate Director, Principal Biostatistician, and Senior Biostatistician, further shaped her expertise in the biopharmaceutical industry. During her tenure at Bristol-Myers Squibb, Prashni contributed to the design and analysis of multiple pivotal clinical trials, demonstrating her skill in managing complex data and deriving actionable insights.
Additionally, Prashni's early career includes impactful roles as an Associate Research Scientist at Yale University and as a Biostatistician at Brown University. These foundational experiences enriched her academic repertoire and provided her with a robust understanding of statistical principles and their applications in medical research. Her scholarly journey has been marked by a deep commitment to advancing statistical science in clinical settings, particularly within oncology, hematology, and beyond.
Education and Achievements
Prashni’s academic accomplishments lay the groundwork for her professional expertise. She earned her Ph.D. in Statistics from the University of Connecticut, where her research enabled her to develop a comprehensive understanding of statistical methodologies and their application in clinical research. Her strong foundation in statistics was further enhanced by obtaining a Master of Science (MSc) in Statistics from the prestigious Indian Institute of Technology, Kanpur. This rigorous academic background equipped her with the necessary skills to tackle complex statistical challenges, particularly those encountered in clinical trial design and analysis.
Over the years, Prashni has honed her skills in various statistical methods including survival analysis, immuno-oncology trial design, multiplicity adjustment, and predictive analysis. She has become proficient in programming languages such as SAS and R, tools that are essential for statistical programming and data analysis in the clinical research field. Her commitment to implementing innovative and cutting-edge methods in clinical development is reflective of her passion for advancing the efficacy and efficiency of clinical trials.
Achievements
Prashni Paliwal's work has been marked by several notable achievements throughout her career. One of her significant accomplishments includes successfully leading multiple Phase 3 trials, which are critical stages in the drug approval process and require meticulous planning and execution to ensure the integrity and reliability of results. Her leadership in these trials has not only provided new therapeutic options for patients but has also helped establish best practices within the industry for clinical trial oversight and execution.
Her knowledge in advanced statistical methods, particularly related to Bayesian inference and predictive analysis, has allowed her to develop innovative approaches to trial design that improve the precision and reliability of outcomes. Prashni is passionate about the integration of innovative analytical techniques that serve to enhance the overall scientific understanding of treatment impacts.
Furthermore, her work extends beyond trial management; Prashni has contributed to the body of knowledge in clinical research through her influential roles in both corporate and academic settings. Her collaboration with esteemed institutions and contributions to research projects underline her ability to bridge the gap between academic theory and practical application in clinical environments.
In summary, Prashni Paliwal exemplifies dedication and excellence in the field of biostatistics and clinical development. Her extensive educational background, coupled with her rich professional experience in oncology, hematology, neuroscience, and other medical specialties, equips her with a unique perspective on the nuances of clinical trial design and statistical analysis. Prashni's relentless pursuit of innovative methods in clinical research continues to contribute to advancements in therapeutic strategies, ultimately aiming to enhance patient outcomes in critical health areas.
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