Pawel Muranski

Assistant Professor Of Medicine; Director of Cellular Immunotherapy Program
New York, New York, United States
Summary
Dr. Pawel Muranski is a distinguished physician-scientist specializing in tumor immunology and T cell-based adoptive immunotherapy for cancer and viral infections. He serves as the lead in developing the cellular therapy program at Columbia University Medical Center, overseeing the establishment of a state-of-the-art GMP manufacturing facility.
In addition to his role at Columbia University Medical Center, Dr. Muranski is a respected investigator at the Columbia Center for Translational Immunology (CCTI). His scientific research delves into the immunobiology of CD4+ T cell subsets and their role in anti-tumor responses, both in murine models and humanized systems.
As a clinician, Dr. Muranski specializes in allogeneic stem cell transplantation and has made significant contributions to the field. He has pioneered the development of multi-virus specific T cells for early prevention of viral reactivation in stem cell transplant recipients and led groundbreaking trials in adoptive immunotherapy for conditions such as Progressive Multifocal Leukoencephalopathy (PML) in immunocompromised patients.
Currently, Dr. Muranski's translational work focuses on generating potent anti-tumor CD4+ T cells that target common and mutated tumor-associated antigens. These cells are utilized in adoptive immunotherapy approaches in both autologous and allogeneic settings, offering promising avenues for cancer treatment.
Dr. Pawel Muranski obtained his Doctor of Medicine (M.D.) degree in Medicine from Akademia Medyczna w Warszawie. He also pursued his education at LIII Liceum Sw. Augustyna.
Throughout his career, Dr. Muranski has held key positions in prestigious organizations. He currently serves as an Assistant Professor Of Medicine, Pathology and Cell Biology, as well as the Director of Cellular Immunotherapy at Columbia University Medical Center. Previously, he contributed as a Staff Clinician at the Hematology Branch of the National Heart, Lung, and Blood Institute and as a Senior Clinical Fellow at the Surgery Branch of the National Cancer Institute.
Prior to his roles at these renowned institutes, Dr. Muranski held positions as a Clinical Fellow in Hematology and Oncology at the NHLBI within the National Institutes of Health, an Attending Physician in Occupational Health at St. Francis Hospital, and a Resident Physician in Internal Medicine at the same institution.