Michael McManus

Professor at University of California, San Francisco

Michael McManus is a distinguished scientist and educator at the University of California, San Francisco (UCSF). Here's a comprehensive overview of his career and accomplishments:

Academic Position

Michael McManus currently holds the position of Full Professor at UCSF.1 2 He is also the Vincent and Stella Coates Endowed Chair at the university.2 4 His primary affiliation is with the Department of Microbiology and Immunology.1 2

Research Focus

Professor McManus is an internationally recognized RNA biologist.1 His research interests span several fields, including:

Noncoding RNA
Functional genomics
Cancer biology
Posttranscriptional gene regulation
Small RNA-mediated regulation of gene expression

His laboratory focuses on dissecting mechanisms of small RNA-mediated regulation of gene expression in mouse models of human disease.1

Career Progression

McManus has had a steady progression in his academic career at UCSF:

Assistant Professor (starting in 2004)
Associate Professor (2010-2016)
Full Professor (2016-present)5

Education and Training

PhD from the University of Alabama in Birmingham, studying RNA editing in Stephen Hajduk's laboratory
Postdoctoral training as a Cancer Research Institute Fellow in the laboratory of Nobel Laureate Phillip Sharp at MIT, focusing on RNAi pathways in mammals1

Affiliations

At UCSF, Dr. McManus is associated with several prestigious centers and institutes:

Helen Diller Comprehensive Cancer Center
Diabetes Center
Eli Edythe Broad Center for Regeneration Medicine and Stem Cell Research
Innovative Genomics Institute2

Research Contributions

Professor McManus has made significant contributions to his field:

Pioneered technologies for high-throughput screening and in vivo genetic perturbation using mouse models
Developed approaches combining synthetic and systems biology to study cancer biology using quantitative methods2
Published extensively, with over 37,000 citations to his work3

Awards and Recognitions

Dr. McManus has received numerous awards for his research excellence and innovative technologies, including:

Sandler Integrative Science Award
New Technologies Award
PBBR Science Award
Breakthrough Technologies Award
WM Keck Award
Robert J. Kleberg, Jr. and Helen C. Kleberg Award2

Michael McManus's work has significantly advanced our understanding of RNA biology, gene regulation, and their implications in human diseases, particularly cancer. His innovative approaches and technological developments have made him a leading figure in his field at UCSF and beyond.