Matthew Goldstein

Husband. Father. Physician-Scientist. Curious.

Matthew Goldstein is a physician-scientist and entrepreneur with extensive experience in the biotech industry. Here are some key details about his background and career:

Education and Training

MD/PhD from Stanford University, where he pioneered novel cancer immunotherapies in Ron Levy's lab
Completed clinical training in Internal Medicine at Harvard Medical School, Brigham & Women's Hospital
Graduate of Swarthmore College

Career Highlights

Currently CEO of JScreen, a genetic screening initiative at Emory University
Previously Head of Immunology at Tango Therapeutics
- Built and led the Immunology program, which became central to Tango's multi-billion dollar partnership with Gilead Sciences
- Served as development head for Tango's lead program that entered clinical trials in 2022
Co-founder of Neon Therapeutics
- Led Translational Medicine and Early Development through first clinical study and IPO
Partner at Related Sciences, a venture creation firm
Spent a decade at Third Rock Ventures building and operating portfolio companies

Personal

Lives in Boston with his wife Myra, daughter Kaia, and son Ezra
Lost his oldest daughter Havi to Tay-Sachs disease in January 2021
This personal tragedy motivated him to become CEO of JScreen to help prevent similar experiences for other families

Matthew Goldstein has built an impressive career combining his medical expertise, scientific research background, and entrepreneurial skills to advance immunology and cancer therapeutics. His personal experience with Tay-Sachs disease has also driven his commitment to genetic screening and disease prevention.1 2