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    Maria Secrier

    Group Leader and Lecturer in Computational Cancer Biology at UCL

    Maria Secrier is an Associate Professor and Group Leader in Computational Cancer Biology at University College London (UCL).2 She leads a research group at the UCL Genetics Institute, focusing on computational cancer genomics and immunology.12

    Secrier's research primarily addresses fundamental questions on somatic evolution in cancer, exploring two main areas:

    1. How mutational processes shape cellular plasticity and adaptation to stress
    2. How cells co-evolve with their microenvironmental niche to evade therapy and persist in tissue1

    Her lab develops and applies cutting-edge statistical modeling, data integration, and machine learning methods to analyze various types of cancer data, including bulk, single-cell, spatial transcriptomics, and digital pathology data.1

    Secrier's educational background includes:

    • Ph.D. in Computational Biology from the European Molecular Biology Laboratory and the University of Heidelberg, Germany
    • B.Sc. in Bioinformatics and Computational Biology from Jacobs University Bremen, Germany3

    Prior to her current role at UCL, Secrier held positions at AstraZeneca as a Senior Scientist and at the Cancer Research UK Cambridge Institute as a Research Associate.3 Her work has contributed significantly to understanding mutational signatures in cancer, immune cell quantification, patient stratification methods, and multi-omics data integration.

    Secrier has published numerous papers in prestigious journals, including Nature Genetics, and her lab has been awarded a UKRI Future Leaders Fellowship to explore mutational processes and spatial context of tumor dormancy.12

    Highlights

    Jun 7 · ucl.ac.uk
    Modelling tumours with experts in India to understand crucial cancer ...
    Modelling tumours with experts in India to understand crucial cancer ...

    Related Questions

    What are some of Maria Secrier's most notable research contributions?
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    Maria Secrier
    Maria Secrier, photo 1
    Maria Secrier, photo 2
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    Location

    Greater Cambridge Area