Luca Gattinoni

Luca Gattinoni is a distinguished professor and researcher in the field of immunotherapy, particularly focused on T-cell-based treatments for cancer. He currently holds the Chair for Functional Immune Cell Modulation at the University of Regensburg, Germany.13 As the Director of the Division of Functional Immune Cell Modulation at the Leibniz Institute for Immunotherapy (LIT), Professor Gattinoni leads research efforts aimed at developing innovative T-cell-based immunotherapies for advanced cancer patients.12

Academic and Professional Background

Professor Gattinoni graduated from the University of Milan School of Medicine with distinction in 1998 and completed his residency in Medical Oncology at the National Cancer Institute of Milan in 2003.1 He then received postdoctoral training at the U.S. National Cancer Institute (NCI), where he remained until 2019, serving in various roles including Staff Scientist and NIH Stadtman Investigator.1

Research Focus

With over 20 years of experience, Professor Gattinoni's research primarily centers on:

1. Elucidating the impact of T-cell differentiation on adoptive T-cell transfer effectiveness in tumor eradication
2. Uncovering and developing unique subsets of T cells with superior therapeutic potential
3. Reprogramming T-cell fate and function through pharmacologic and genetic interventions

His work has significantly contributed to the current understanding of early memory T cells' superior therapeutic potential compared to cytotoxic effector T cells in cancer treatment.1

Achievements and Honors

Professor Gattinoni has:

• Published more than 100 manuscripts in his field
• Received several prestigious awards, including the SITC Presidential Award (2004) and the NCI Director's Intramural Innovation Award (2013)
• Established a clinical-grade manufacturing platform for CAR-modified T memory stem cells (Tscm)
• Initiated a first-in-human study to test donor-derived CD19-CAR Tscm cells1

Current Roles

In addition to his academic position, Professor Gattinoni serves as:

• Director of the Division of Functional Immune Cell Modulation at LIT12
• Project coordinator for T-FITNESS, a research initiative45
• Honorary professor at the Amity Institute of Molecular Medicine and Stem Cell Research, Amity University, Noida, India1

Professor Gattinoni's LinkedIn username is indeed luca-gattinoni-b423a810, as mentioned in the query.4