Lisa Ensign

Lisa Ensign is a highly experienced biostatistician and clinical science expert currently serving as the Vice President of the Statistical Innovation Group at Medidata Solutions, a Dassault Systèmes company.1 With over two decades of experience in the field, she brings a wealth of knowledge and expertise to her role.

Education and Background

Lisa Ensign holds impressive academic credentials:

• BS in Mathematics, Psychology, and Genetics from Stetson University, where she graduated summa cum laude as valedictorian1
• MS in Biostatistics from Harvard University, where she was an NIH Fellowship recipient1
• PhD in Clinical Science with a focus on Health Information Technology from the University of Colorado Anschutz Medical Campus1

Professional Experience

Throughout her career, Lisa has held several notable positions:

• Vice President, Statistical Innovation Group at Medidata Solutions (January 2022 - Present)1
• Senior Director of Statistics at Medidata Solutions (September 2016 - January 2022)1
• Instructor at CU Denver | Anschutz Graduate School (August 2017 - Present)1
• Biostatistics, Analytics, and Data Management Consultant at Significant Statistics, LLC (2009 - 2016)1

Expertise and Focus

Lisa's work primarily centers on:

• Improving the safety and efficacy of clinical trials
• Developing analytical approaches to enhance the efficiency and rigor of clinical trials
• Creating external control arms and synthetic control arms
• Applying machine learning and natural language processing techniques
• Risk-based monitoring and quality management in clinical trials
• Software system development and validation

She is particularly passionate about projects that aim to improve clinical trial safety and efficacy, with a focus on using external controls to enhance trial design and analysis.1

Additional Roles

In addition to her primary role at Medidata Solutions, Lisa also serves as an instructor on ethics and responsible conduct of research at the University of Colorado.1