Enrico Moiso

Enrico Moiso is a Postdoctoral Associate at the MIT Koch Institute for Integrative Cancer Research, specializing in molecular medicine and cancer research.3 His work focuses on identifying rare metastatic cell states in cholangiocarcinoma and other tumors as part of the Garg Laboratory.1

Moiso has made significant contributions to cancer research, particularly in the field of undiagnosable cancers. He was the lead author of a study published in Cancer Discovery on August 30, 2022, which introduced a new deep-learning approach to identify cancers of unknown primary.2 This artificial intelligence tool, developed in collaboration with researchers from MIT and Massachusetts General Hospital, can classify cancer types with high sensitivity and accuracy.2

The research led by Moiso involved comparing two large cell atlases: the Cancer Genome Atlas (TCGA) and the Mouse Organogenesis Cell Atlas (MOCA). This comparison allowed them to identify correlations between tumor and embryonic cells, leading to a novel method of profiling and identifying tumors.2

Prior to his position at MIT, Moiso gained extensive experience in both laboratory and computational biology techniques.3 His current work at the Koch Institute began in September 2018 and is expected to continue until August 2023.4

Moiso's research has potential implications for personalized medicine in cancer treatment. By integrating developmental gene expression data with other types of information, such as radiology and pathology, his work aims to improve cancer diagnosis and treatment strategies.2