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    Constance Cepko

    Professor of Genetics at Harvard Medical School

    Constance Cepko is a Professor of Genetics and Ophthalmology at Harvard Medical School and an Investigator at the Howard Hughes Medical Institute. Her research focuses on understanding retinal development and degeneration, with a goal of developing gene therapies to prevent blindness.126

    Education and Early Career

    • B.S. in Biochemistry and Microbiology: University of Maryland College of Computer, Mathematical, and Natural Sciences.1
    • Ph.D.: Massachusetts Institute of Technology (1982), advised by Nobel laureate Phil Sharp, studying adenovirus capsid assembly.14
    • Postdoctoral Work: Trained with Richard C. Mulligan at MIT, pioneering retroviral vectors for gene transduction in the nervous system.148

    Research Contributions

    • Retinal Development: Investigates molecular mechanisms guiding cell fate determination in the retina, including photoreceptor diversification and retinal circuitry formation.256
    • Gene Therapy: Develops treatments for inherited retinal degenerations (e.g., retinitis pigmentosa) by targeting photoreceptor survival.478
    • Technological Innovations: Created electroporation methods for gene delivery and tools like nanobodies to manipulate intracellular processes.256

    Awards and Honors

    • National Academy of Sciences (elected 2002).1
    • Bressler Prize in Vision Science (2011) for contributions to retina development.12
    • Alcon Research Institute Award and David Cogan Award for advancements in vision science.26

    Current Roles

    • Bullard Professor of Genetics and Neuroscience at Harvard.35
    • Howard Hughes Medical Institute Investigator since 1994.6
    • Leads the Cepko Lab, which combines genomic analysis, viral tools, and gene therapy to study retinal biology.57

    Her work has been published in top journals like Cell and Nature Neuroscience, and she is recognized for mentoring excellence, including the A. Clifford Barger Excellence in Mentoring Award.26

    Highlights

    Constance Cepko, PhD - Harvard Ophthalmology
    Constance Cepko, PhD - Harvard Ophthalmology
    Jan 1 · hhmi.org
    Constance L. Cepko, PhD | Investigator Profile | 1994-Present - HHMI
    Constance L. Cepko, PhD | Investigator Profile | 1994-Present - HHMI
    Sep 1 · amacad.org
    Constance Louise Cepko | American Academy of Arts and Sciences
    Constance Cepko - Harvard Genetics Department
    Constance Cepko - Harvard Genetics Department
    Jan 1 · hsci.harvard.edu
    Constance Cepko, Ph.D. | Harvard Stem Cell Institute (HSCI)
    Constance Cepko, Ph.D. | Harvard Stem Cell Institute (HSCI)
    Constance Cepko, PhD - InsideScientific
    Constance Cepko, PhD - InsideScientific
    Constance Cepko, PhD - Mass General Advances in Motion
    ‪Constance L Cepko‬ - ‪Google Scholar‬
    May 15 · en.wikipedia.org
    Constance Cepko - Wikipedia

    Related Questions

    What are some of Constance Cepko's most significant contributions to developmental biology?
    How does Constance Cepko's work on gene therapy for blindness progress?
    What awards and honors has Constance Cepko received for her research?
    Can you explain the electroporation method developed by Constance Cepko?
    What is the role of the Howard Hughes Medical Institute in Constance Cepko's research?
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    Location

    Newton Highlands, Massachusetts, United States