Carl June

Notable American immunologist and oncologist

Carl H. June is a prominent immunologist and oncologist, currently serving as the Richard W. Vague Professor in Immunotherapy at the Perelman School of Medicine, University of Pennsylvania. He is also the Director of the Center for Cellular Immunotherapies and the Parker Institute for Cancer Immunotherapy at the same institution.1 2

Education and Training

Undergraduate: Graduated from the United States Naval Academy with a B.S. in Biology (1975).
Medical Degree: Obtained his M.D. from Baylor College of Medicine (1979).
Postgraduate Training: Completed clinical training in internal medicine and medical oncology at the National Naval Medical Center, followed by postdoctoral research at the Fred Hutchinson Cancer Research Center, focusing on transplantation biology.1 2 4

Research Contributions

Dr. June is widely recognized for his pioneering work in T-cell therapies, particularly in developing Chimeric Antigen Receptor (CAR) T-cell therapy. His laboratory was instrumental in creating CAR T cells that have been used successfully to treat various cancers, including chronic lymphocytic leukemia and acute lymphoblastic leukemia. In 2017, his team's CAR T-cell therapy became the first gene therapy approved by the FDA.1 2 4

Honors and Achievements

He has published over 400 manuscripts and received numerous accolades, including:

Election to the Institute of Medicine (2012) and the American Academy of Arts and Sciences (2014).
The Paul Ehrlich and Ludwig Darmstaedter Prize, shared with James Allison.
Recognition as one of Time Magazine's 100 Most Influential People (2018) and numerous other awards for his contributions to cancer research.2 4

Current Role

In addition to his teaching and research responsibilities, Dr. June leads a laboratory focused on advancing cellular therapies for cancer and chronic infections, emphasizing translational research that bridges laboratory findings with clinical applications.1 2 5

For more details about his work and contributions, you can find him on LinkedIn under the username carl-june-03154214.3