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Omar Abudayyeh
Assistant Professor at Harvard Medical School / Brigham and Women's Hospital / MGB Gene and Cell Therapy Institute
Omar Abudayyeh is an Assistant Professor at Harvard Medical School and an Investigator at Brigham and Women's Hospital, affiliated with the Mass General Brigham Gene and Cell Therapy Institute. He also serves as a faculty member in the Department of Stem Cell and Regenerative Biology at Harvard University. His research focuses on developing innovative molecular technologies for gene editing, diagnostics, and therapeutics, particularly utilizing CRISPR systems to address challenges in genetic diseases, cancer, aging, and regenerative medicine.
Education and Early Career
Abudayyeh completed his undergraduate studies at the Massachusetts Institute of Technology (MIT), earning a Bachelor of Science in Mechanical Engineering and Biological Engineering in 2012. He then pursued an MD/PhD program at Harvard Medical School, where he completed his PhD in 2018 under the mentorship of Feng Zhang at the Broad Institute. His doctoral research concentrated on discovering novel CRISPR enzymes for applications in genome editing and diagnostics.123
Research Focus
At Harvard, Abudayyeh leads the Abudayyeh-Gootenberg Lab, which is dedicated to exploring programmable systems in biology. The lab's work encompasses several key areas:
- Gene Editing: Developing next-generation tools for precise genome manipulation.
- Cellular Aging: Investigating molecular mechanisms of aging to inform regenerative therapies.
- Artificial Intelligence: Applying machine learning to enhance protein design and predict cellular behavior.
- Diagnostics: Innovating CRISPR-based diagnostic technologies for healthcare applications.456
Achievements and Recognition
Abudayyeh has received numerous accolades for his contributions to biomedical research, including being named a Technology Review Innovators Under 35 and featured in Forbes' 30 Under 30 list. He has also been recognized as a TEDMED Hive honoree and a Paul and Daisy Soros Fellow. His work continues to influence the fields of gene therapy and molecular diagnostics significantly.234
In addition to his academic roles, he is a co-founder of Sherlock Biosciences, a company focused on commercializing CRISPR-based diagnostic tools.12
Highlights
Beautifully put.
So true
New lab preprint! 🚀
Modeling complex data distributions is tough.
We designed GDEs, a new framework that tackles this head-on!
GDEs generalize across text, images & MANY bio apps (think virtual cells, spatial bio, viral genome tracking). Thread 👇

